Ethyl 6-azidohexanoate
6-Azidohexanoic acid ethyl ester
CAS: 65374-10-9
Molecular Formula: C8H15N3O2
Ethyl 6-azidohexanoate - Names and Identifiers
| Name | 6-Azidohexanoic acid ethyl ester |
| Synonyms | Ethyl 6-azidohexanoate 6-Azidohexanoic acid ethyl ester |
| CAS | 65374-10-9 |
Ethyl 6-azidohexanoate - Physico-chemical Properties
| Molecular Formula | C8H15N3O2 |
| Molar Mass | 185.2236 |
Ethyl 6-azidohexanoate - Introduction
6-Azidohexanoic acid ethyl ester(6-Azidohexanoic acid ethyl ester) is an organic compound with the chemical formula C8H15N3O2. It is a colorless liquid with a spicy fragrance. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: colorless liquid
-Molecular weight: 185.23g/mol
-Boiling point: 173-174 ℃
-Density: 1.06g/cm³
-Melting point:-34 ℃
-Flammability: Flammable
Use:
6-Azidohexanoic acid ethyl ester is an important intermediate compound with many applications in organic synthesis and chemical biology research:
-Azide reaction: It can be used as a source of azide groups, and can participate in azide reaction to generate compounds with azide groups.
-Biomarkers and biological cross-linking: Azido-based compounds can be used for the study of biomarkers and biological cross-linking, such as fluorescent labeling and protein cross-linking.
-Drug research: 6-Azidohexanoic acid ethyl ester can be used as an intermediate in drug research to synthesize compounds with specific activities.
Preparation Method:
The preparation method of 6-Azidohexanoic acid ethyl ester can be obtained by the following steps:
1. First, a suspension of sodium azide and ethyl n-caproate was slowly added to dimethyl sulfoxide in an ice bath while the reaction was stirred.
2. After completion of the reaction, the resulting mixture was filtered and washed to obtain the product.
3. Finally, the product was purified by distillation and crystallization.
Safety Information:
As with other azido compounds, the handling of 6-Azidohexanoic acid ethyl ester requires caution and in accordance with relevant safety procedures. Here are some safety considerations:
-Avoid inhalation, ingestion or contact with skin and eyes.
-Wear appropriate personal protective equipment such as lab gloves, goggles and protective clothing during operation.
-Operate in a well-ventilated place and avoid contact with organic matter and other combustibles.
-should be stored away from fire and high temperature, stored in a cool, dry place.
-Before using or handling 6-Azidohexanoic acid ethyl ester, you should understand its safety operation methods and risk assessment in detail, and comply with relevant regulations and safety guidelines.
Nature:
-Appearance: colorless liquid
-Molecular weight: 185.23g/mol
-Boiling point: 173-174 ℃
-Density: 1.06g/cm³
-Melting point:-34 ℃
-Flammability: Flammable
Use:
6-Azidohexanoic acid ethyl ester is an important intermediate compound with many applications in organic synthesis and chemical biology research:
-Azide reaction: It can be used as a source of azide groups, and can participate in azide reaction to generate compounds with azide groups.
-Biomarkers and biological cross-linking: Azido-based compounds can be used for the study of biomarkers and biological cross-linking, such as fluorescent labeling and protein cross-linking.
-Drug research: 6-Azidohexanoic acid ethyl ester can be used as an intermediate in drug research to synthesize compounds with specific activities.
Preparation Method:
The preparation method of 6-Azidohexanoic acid ethyl ester can be obtained by the following steps:
1. First, a suspension of sodium azide and ethyl n-caproate was slowly added to dimethyl sulfoxide in an ice bath while the reaction was stirred.
2. After completion of the reaction, the resulting mixture was filtered and washed to obtain the product.
3. Finally, the product was purified by distillation and crystallization.
Safety Information:
As with other azido compounds, the handling of 6-Azidohexanoic acid ethyl ester requires caution and in accordance with relevant safety procedures. Here are some safety considerations:
-Avoid inhalation, ingestion or contact with skin and eyes.
-Wear appropriate personal protective equipment such as lab gloves, goggles and protective clothing during operation.
-Operate in a well-ventilated place and avoid contact with organic matter and other combustibles.
-should be stored away from fire and high temperature, stored in a cool, dry place.
-Before using or handling 6-Azidohexanoic acid ethyl ester, you should understand its safety operation methods and risk assessment in detail, and comply with relevant regulations and safety guidelines.
Last Update：2024-04-09 21:01:54
